Category: COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Sex-Based and Genetic Vulnerabilities: Hormonal Modulation, IL-6 Polymorphisms, HLA Factors, and Personalized Medicine Implications

Sex-Based and Genetic Vulnerabilities: Hormonal Modulation, IL-6 Polymorphisms, HLA Factors, and Personalized Medicine Implications

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a striking female predominance and heterogeneous symptom profiles. Emerging evidence suggests…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics

Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics

Grant McGee Talkington, Paresh Kolluru, Timothy E. Gressett, et. al., Frontiers in Neurology One lingering effect of the COVID-19 pandemic created by SARS-CoV-2 is the emergence of Long COVID (LC),…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Persistent SARS-CoV-2 Spike Protein: Genomic Modulation, Immune Dysregulation, and Impaired Antibody Maturation

Persistent SARS-CoV-2 Spike Protein: Genomic Modulation, Immune Dysregulation, and Impaired Antibody Maturation

Author: John Murphy, CEO COVID 19 Long-haul Foundation Abstract The SARS-CoV-2 spike glycoprotein, central to viral entry and the target of mRNA vaccine platforms, has emerged as a persistent antigen…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Long-Term Outcomes and Mortality Risk: Cardiovascular Sequelae, Actuarial Modeling, and Public Health Implications

Long-Term Outcomes and Mortality Risk: Cardiovascular Sequelae, Actuarial Modeling, and Public Health Implications

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic condition with significant long-term health consequences. This article…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Post-Vaccination Spike Protein Migration: Genomic Mechanisms of Motility, Pathological Spread, and Long-Term Implications

Post-Vaccination Spike Protein Migration: Genomic Mechanisms of Motility, Pathological Spread, and Long-Term Implications

Author: John Murphy, M.D. CEO Covid-19 Long-haul Foundation Abstract Messenger RNA (mRNA) vaccines have revolutionized infectious disease prevention, offering rapid deployment and robust immunogenicity. However, emerging evidence suggests that the…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Genomic Convergence: Emerging Pathways, Mechanisms, and Druggable Targets in Precision Medicine for COVID Long-haul Research

Genomic Convergence: Emerging Pathways, Mechanisms, and Druggable Targets in Precision Medicine for COVID Long-haul Research

Author: John Murphy, CEO COVID-19 Long-haul Foundation Abstract The past three years have witnessed an unprecedented acceleration in genomic discovery, driven by advances in single-cell sequencing, spatial transcriptomics, and integrative…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring

Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis…[...]

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